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Profiles of undergraduate researchers


Bradley Buran
Zoology & Cultural Anthropology

Hojun Li
Biochemistry & Mathematics


Esteban Carrizosa
Cell & Molecular Biology & Genetics




Bradley Buran has been conducting undergraduate research in the Department of Biology now for one year. He was first introduced to research when in high school he became a volunteer at the National Institute of Deafness and Other Communication Disorders (NIDCD) of the National Institutes of Health. Wanting to find a laboratory position closer to campus, he searched for a faculty member with research interests similar to his own, and began to work for Dr. Arthur Popper. His research focuses on auditory neurobiology of deep-sea fish, and has recently been awarded a Goldwater Fellowship. He receives funding for his research through the HHMI Undergraduate research fellowship program and the NIDCD.

"Deep-sea fish are so different from more common shallow-water species in terms of morphology and ultrastructure. Often the ears of deep-sea fish have very intricate otoliths (ear stones) and unique sensory cilia that are very fascinating (and beautiful to an otolaryngologist). It's kind of neat to know that even though I'm an undergraduate student, I'm finding stuff that no one else has ever seen before."  

Brad says that the lab environment is very friendly. "We all help each other with experiments, and discuss our research to see if anyone else has any ideas. This gives me valuable experience and a good background for the future. However, the most important part of my research in Dr. Popper's lab is the networking opportunities I receive, as I have been introduced to quite a few people in my field of interest."  

"My mentor has been very supportive of my research and has provided valuable guidance and advice, not just with my research, but also with helping me find a graduate-level position. In addition, the graduate, doctoral, and post-doctoral students in the lab are often willing to talk to the undergraduate students and give them advice about graduate school."

Brad's plans for the future include graduating in May 2003, and focusing his research on developmental neurobiology of the auditory system. Although his particular field of interest may change, he plans to go to graduate school and complete a doctoral degree.



Hojun Li became interested in research as a result of taking Organic Chemistry. He started looking for a research position at the end of his first semester, and on the recommendation of a laboratory teaching assistant, he decided to pursue a position in Dr. Jeffery Davis' lab. There he studies the self-assembly properties of the guanosine DNA base, and its potential as an artificial ion channel through cell membranes.







 


"What I find most interesting about my research is how much of a phenomena chemical reactions are. It is incredible to study why certain elements will bond with some elements and not others, and it is even more incredible to study why certain types of compounds will bond with themselves to create really elaborate structures," he says.






One of Hojun's favorite aspects of research is his interaction with his mentor and others in the lab. "Its great to meet all these different types of people who are all incredibly intelligent and know so much about chemistry and science in general. What's really nice is that my mentor and the graduate students in the lab all treat us undergrads as equals."





He's been awarded a Howard Hughes Fellowship, which has allowed him to pursue further research in Dr. Davis' lab, and is currently planning on attending medical school. Hojun says that research has "helped me in pursuing my career goals by giving me exposure to what 'real science' is, rather than the very carefully packaged information that students are given in undergraduate science classes." He plans to graduate in Spring 2005, with Departmental Honors in both Biochemistry and Math.



 

Esteban Carrizosa has always been interested in how microorganisms can cause disease. After speaking with his advisor about pursuing undergraduate research, he decided to contact some professors in the Department of Cell Biology and Molecular Genetics, where he chose to work in the laboratory of Dr. Daniel Stein. Dr. Stein and his colleagues study the human pathogen Neisseria gonorrhoeae. His project involves developing a system to study spontaneous mutation frequencies in the gonococcus.



"My research is interesting in that it is a small step toward understanding how the gonococcus, as a pathogen primarily transmitted through sexual contact, can vary its DNA, and consequently its outer surface antigens, to adapt to a wide variety of environmental conditions."


Working in Dr. Stein's lab has exposed Esteban to various facets of research including molecular biology, immunology, and microbiology. He really enjoys the lab environment. "Dr. Stein is very helpful and the other people in the lab are great to be around."

 




Esteban presented a poster detailing his research at the 13th International Pathogenic Neisseria Conference in Oslo, Norwayin September 2002. As far as long-term plans go, he intends to pursue a Ph.D. in immunology or cell biology. "I now know that I like research, and that it's what I want to do with my life. I understand how difficult research is, which is very valuable. A lot of people come in expecting scientific research to be easy, and it's not." He will graduate in the spring of 2003, with Departmental Honors in Cell Biology and Molecular Genetics.


UMD
COLLEGE OF CHEMICAL & LIFE SCIENCES*UNIVERSITY OF MARYLAND* COLLEGE PARK, MD 20742
e-mail: life@umd.edu Tel.: 301.405.2080