Emily English, Ph.D.

English Email
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To Emily English chemistry is a hobby and a profession. As an undergraduate at UM she showed enormous promise, a promise that has been realized. She has experience in organic synthesis and in protein chemistry. Her fondest wish is to see her love of chemistry develop in the students she teaches. 

Education

2007

 Ph.D. Chemistry University of Wisconsin, Madison, WI
2002 B.S. Magna Cum Laude with Honors in Chemistry University of Maryland, College Park, MD
Awards
2006 Leah Cohodas Berk Award for Excellence in Chemistry Research, Department of Chemistry, University of Wisconsin, Madison
2006 Travel award - International Conference on Antiviral Research, San Juan, Puerto Rico
2005 McElvain Travel Award – Department of Chemistry, University of Wisconsin - Madison
2005-2006 NIH Chemistry and Biology Interface Traineeship, University of Wisconsin, Madison
2001 Goldwater Scholarship
2001 Phi Beta Kappa
2000-2002 Howard Hughes Medical Institute Undergraduate Research Fellowship
Technical Skills:
Organic synthesis, small molecule purification, solid-phase peptide synthesis, HPLC purification of peptides and small molecules, NMR characterization of small molecules and peptides, tissue culture, cell-based assay development, protein expression

Publications:

Akkarawongsa, R.; Potocky, T. B.; English, E. P.; Gellman, S. H.; Brandt, C. R. Inhibition of Herpes Simplex Virus Type 1 Infection by Cationic b-Peptides, Antimicrob. Agents Chemother. 2008, 52, 2120-2129.

Chi, Y.; English, E. P.; Pomerantz, W. C.; Horne, S. H.; Joyce, L. A.; Alexander, L. R.; Fleming, W. S.; Hopkins, E. A.; Gellman, S. H. Practical Synthesis of Enantiomerically Pure β2-Amino Acids via Proline-Catalyzed Diastereoselective Aminomethylation of Aldehydes, J. Am. Chem. Soc. 2007, 129, 6050-6055.

English, E. P.; Chumanov, R. S.; Gellman, S. H.; Compton, T. Rational Development of β-Peptide Inhibitors of Human Cytomegalovirus Entry, J. Biol. Chem. 2006, 281, 2661-2667.

Peelen, T. J.; Chi, Y.; English, E. P.; Gellman, S. H. Synthesis of 4,4-Disubstituted 2-Aminocyclopentanecarboxylic Acid Derivatives and Their Incorporation into 12-Helical β-Peptides. Org. Lett. 2004, 6, 4411-4414.

Dupont, J.; Bemish, R. J; McCarthy, K. E.; Payne, E. R.; Pollard, E. B.; Ripin, D. H. B.; Vanderplas, B. C.; Watrous, R. M. Oxidation of carbamate-protected alkylhydrazines to the corresponding hydrazones under Swern conditions. Tetrahedron Lett. 2001, 42, 5587.

Patents:

“Concise Beta2-Amino Acid Synthesis Via Organocatalytic Aminomethylation” Chi, Y.; Gellman, S. H.; Pomerantz, W. C.; Horne, W. S.; Guo, L.; English, E. P. US Patent Pending.

“Beta-Polypeptides That Inhibit Cytomegalovirus Infection” Compton, T.; Gellman, S. H.; English, E. P.; Chumanov, R. S. U.S. Patent P05279US.