Functional Genomics



1. In Gibson and Muse read pp. 212-236

2. Read the following two papers:


Gates, J. and Thummel, C. 2000 An Enhancer Trap Screen for Ecdysone-Inducible Genes Required for Drosophila Adult Leg Morphogenesis. Genetics 156:1765-1776 [PDF]

Lohmann, J.U., Endl, I. and Bosch, T.C.G. 1999 Silencing of Developmental Genes in Hydra. Developmental Biology 214:211-214 [PDF]


We would also like the class to consider two issues for discussion:

1. How they would apply one of these functional genomics techniques to their own research.

2. What are the limitations of these techniques, e.g., what false results may be generated or what functional genomics questions could not be answered.

Thanks!
Alli and Hrrbo