Information for Evolutionary Genomics/Differential Display

Read pages 148-158

Be prepared to discuss question #4. If you are actively involved in research
would transcriptional profiling (i.e. differential display, SAGE, etc) be
useful to you?? If not, why not ? If you arenít actively involved in
research but have evolutionary interests, do you think these methods would
be useful in addressing those interests? Again, why or why not?

Also read

Moore, RC et al. 2003 Genetic and functional analysis of DD44, a sex-linked gene from the dioecious plant Silene latifolia provides clues to early events in sex chromosome evolution. Genetics 163:321-334. [PDF]

If you are interested in more information regarding the techniques, the following sites are helpful.

http://www.genhunter.com/products/differential/

GenHunter Corporation was founded in 1992, the year when differential
display was invented, to provide the biomedical research community easy
access to the technology.

SAGE ANALYSIS
http://www.sagenet.org
http://www.ncbi.nlm.nih.gov/SAGE

MICROBEAD TECHNOLOGY
http://www.lynxgen.com