Pros and Cons of Microarrays

Guest presentation by Eric Baehrecke

Before class, read the following papers:

1) Eisen, M.B., Spellman, P., Brown, P. and Botstein, D. 1998 Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. USA 95:14863-14868. [PDF]

2) Lee, C.-Y., Clough, E.A., Yellon,P., Teslovich, T.M., Stephan, D.A. and Baehrecke, E.H. 2003 Genome-Wide Analyses of Steroid and Radiation-Triggered Programmed Cell Death in Drosophila. Current Biology 13:350-357 [PDF]

3) Stathopoulos, A., Van Drenth, M., Erives, A., Markstein, M. and Levine, M. 2002 Whole-Genome Analysis of Dorsal-Ventral Patterning in the Drosophila Embryo morphogenesis. Cell 111:687-701. [PDF]