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titleboxPATRICK KANOLD titlebox

professor pictureAssistant Professor

email:pkanold@umd.edu
phone:
301.405.5741 (office)
301.405.3145 (lab)
fax:301.314.9358
office:1116 Bioscience Research Building
graduate programs: Biology, C-CEBH, NACS
bullet visit lab page   bullet most recent publications


RESEARCH INTERESTS

Dr. Kanold studies the development and plasticity of the brain, in particular how periods of learning and plasticity are initiated and controlled. His work focuses on the development of the central auditory and visual system in particular on the role of early cortical circuits in brain wiring. He uses advanced neurophysiological, imaging, molecular and computational techniques. His work furthers our understanding of how prenatal and postnatal brain injury contribute to neurodevelopmental disorders such as cerebral palsy, epilepsy and schizophrenia.

Recent Publications


Kanold PO, Manis PB. Encoding the timing of inhibitory inputs. J Neurophysiol. 2005 May;93(5):2887-97. Epub 2004 Dec 29.

Tagawa Y, Kanold PO, Majdan M, Shatz CJ. Multiple periods of functional ocular dominance plasticity in mouse visual cortex. Nat Neurosci. 2005 Mar;8(3):380-8. Epub 2005 Feb 20.

Atzori M, Kanold PO, Pineda JC, Flores-Hernandez J, Paz RD. Dopamine prevents muscarinic-induced decrease of glutamate release in the auditory cortex. Neuroscience. 2005;134(4):1153-65.

Syken J, Grandpre T, Kanold PO, Shatz CJ. PirB restricts ocular-dominance plasticity in visual cortex. Science. 2006 Sep 22;313(5794):1795-800. Epub 2006 Aug 17.

Kanold PO, Shatz CJ. Subplate neurons regulate maturation of cortical inhibition and outcome of ocular dominance plasticity. Neuron. 2006 Sep 7;51(5):627-38.

Butts DA, Kanold PO, Shatz CJ. A burst-based "Hebbian" learning rule at retinogeniculate synapses links retinal waves to activity-dependent refinement. PLoS Biol. 2007 Mar;5(3):e61..