Structure and Voltage-Gating of VDAC:

Thomas, L., Blachly-Dyson, E., Colombini, M., and Forte, M. 1993. Mapping of residues forming the voltage sensor of the VDAC ion channel. Proceedings of the National Academy of Sciences U.S.A., 90: 5446-5449.

Song, J. and Colombini, M. 1996. Indications of a common folding pattern for VDAC channels from all sources. Journal of Bioenergetics and Biomembranes, 28:153-161.

Song, J., Midson, C., Blachly-Dyson, E., Forte, M., and Colombini, M. 1998. The sensor regions of VDAC are translocated from within the membrane to the surface during the gating processes. Biophysical Journal, 74: 2926-2944.  Full Text

Song, J., Midson, C., Blachly-Dyson, E., Forte, M., and Colombini, M. 1998. The topology of VDAC as probed by biotin modification. Journal of Biological Chemistry, 273:24406-24413.  Full Text

Zizi, M., Byrd, C., Boxus, R., and Colombini, M. 1998. The voltage-gating process of the VDAC channel is sensitive to ion flow. Biophysical Journal, 75: 704-713.

Levadny, V., Colombini, M., Li, X.X. and Aguilella, V.M.  2002. Electrostatics explains the shift in VDAC gating with salt activity gradient. Biophysical Journal, 82:1773-83.

Komarov, A.G., Graham, B.H., Craigen, W.J., and Colombini, M. 2004. The physiological properties of a novel family of VDAC-like proteins from Drosophila melanogaster. Biophysical Journal, 86:152-162.   Full Text

 

Hiller, S., Garces, R.G., Malia, T.J. Orekhov, V.Y., Colombini, M. and Wagner, G. 2008. Solution structure of the integral human membrane protein VDAC-1 in detergent micelles. Science 321: 1206-1210.    Full Text    


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